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Specific signals at the 3′ end of the DHFR gene define one boundary of the downstream origin of replication

The Chinese hamster dihydrofolate reductase (DHFR) origin of replication consists of a 55-kb zone of potential initiation sites lying between the convergently transcribed DHFR and 2BE2121 genes. Two subregions within this zone (ori-β/ori-β′ and ori-γ) are preferred. In the DHFR-deficient variant, DR...

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Detalhes bibliográficos
Main Authors: Mesner, Larry D., Hamlin, Joyce L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091740/
https://ncbi.nlm.nih.gov/pubmed/15879555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1307105
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