טוען...
The Proton-Pump Inhibitor Lansoprazole Enhances Amyloid Beta Production
A key event in the pathogenesis of Alzheimer’s disease (AD) is the accumulation of amyloid-β (Aβ) species in the brain, derived from the sequential cleavage of the amyloid precursor protein (APP) by β- and γ-secretases. Based on a systems biology study to repurpose drugs for AD, we explore the effec...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592824/ https://ncbi.nlm.nih.gov/pubmed/23520537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058837 |
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