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Pharmacokinetics and effect on caffeine metabolism of the proton pump inhibitors, omeprazole, lansoprazole, and pantoprazole

AIMS: To study the pharmacokinetics of three proton pump inhibitors, omeprazole, lansoprazole, and pantoprazole, as well as any potential influence on CYP1A2 activity (measured by means of rate of caffeine metabolism) of these compounds at single dose and repeated dose administration. METHODS: Fourt...

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Autors principals: Andersson, Tommy, Holmberg, Johan, Röhss, Kerstin, Walan, Anders
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873971/
https://ncbi.nlm.nih.gov/pubmed/9578184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.t01-1-00702.x
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