A multicentre prospective study evaluating the impact of proton‐pump inhibitors omeprazole and pantoprazole on voriconazole plasma concentrations

Voriconazole is an antifungal metabolised by CYP2C19 enzyme, which can be inhibited by proton‐pump inhibitors (PPIs). A prospective observational study was carried out to determine the influence of PPIs on voriconazole pharmacokinetic. The 78 patients included were divided into 4 groups: omeprazole...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Blanco Dorado, Sara, Maroñas Amigo, Olalla, Latorre‐Pellicer, Ana, Rodríguez Jato, María Teresa, López‐Vizcaíno, Ana, Gómez Márquez, Aurea, Bardán García, Belén, Belles Medall, Dolores, Barbeito Castiñeiras, Gema, Pérez del Molino Bernal, María Luisa, Campos‐Toimil, Manuel, Otero Espinar, Francisco, Blanco Hortas, Andrés, Zarra Ferro, Irene, Carracedo, Ángel, Lamas, María Jesús, Fernández‐Ferreiro, Anxo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Short Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176997/
https://ncbi.nlm.nih.gov/pubmed/32110830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14267
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