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Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole

BACKGROUND: The pharmacokinetics of proton pump inhibitors (PPIs) may be affected by food intake. We aimed to evaluate the effect of food on the pharmacokinetics of omeprazole, rabeprazole, and pantoprazole. SETTING: The study population comprised 186 healthy volunteers participating in 6 bioequival...

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Pubblicato in:BMC Pharmacol Toxicol
Autori principali: Ochoa, Dolores, Román, Manuel, Cabaleiro, Teresa, Saiz-Rodríguez, Miriam, Mejía, Gina, Abad-Santos, Francisco
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382816/
https://ncbi.nlm.nih.gov/pubmed/32711578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00433-2
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