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Lack of drug interaction between omeprazole, lansoprazole, pantoprazole and theophylline

AIMS: Theophylline is a model substrate of cytochrome P4501A2. The ability of the proton pump inhibitors (PPI) omeprazole, lansoprazole and pantoprazole to induce cytochrome P4501A2 has not yet been unequivocally resolved. The aim of this comprehensive study was to compare directly the effect of the...

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Detalhes bibliográficos
Main Authors: Dilger, Karin, Zheng, Zhichang, Klotz, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014345/
https://ncbi.nlm.nih.gov/pubmed/10510158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00043.x
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