A carregar...

Druggable Protein Interaction Sites Are More Predisposed to Surface Pocket Formation than the Rest of the Protein Surface

Despite intense interest and considerable effort via high-throughput screening, there are few examples of small molecules that directly inhibit protein-protein interactions. This suggests that many protein interaction surfaces may not be intrinsically “druggable” by small molecules, and elevates in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Johnson, David K., Karanicolas, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591273/
https://ncbi.nlm.nih.gov/pubmed/23505360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002951
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!