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Are protein–protein interfaces more conserved in sequence than the rest of the protein surface?
Protein interfaces are thought to be distinguishable from the rest of the protein surface by their greater degree of residue conservation. We test the validity of this approach on an expanded set of 64 protein–protein interfaces using conservation scores derived from two multiple sequence alignment...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286531/ https://ncbi.nlm.nih.gov/pubmed/14691234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03323604 |
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