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Are protein–protein interfaces more conserved in sequence than the rest of the protein surface?
Protein interfaces are thought to be distinguishable from the rest of the protein surface by their greater degree of residue conservation. We test the validity of this approach on an expanded set of 64 protein–protein interfaces using conservation scores derived from two multiple sequence alignment...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286531/ https://ncbi.nlm.nih.gov/pubmed/14691234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03323604 |
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