Yüklüyor......
Selectivity by Small-Molecule Inhibitors of Protein Interactions Can Be Driven by Protein Surface Fluctuations
Small-molecules that inhibit interactions between specific pairs of proteins have long represented a promising avenue for therapeutic intervention in a variety of settings. Structural studies have shown that in many cases, the inhibitor-bound protein adopts a conformation that is distinct from its u...
Kaydedildi:
| Yayımlandı: | PLoS Comput Biol |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2015
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338137/ https://ncbi.nlm.nih.gov/pubmed/25706586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004081 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|