A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus

Presently, respiratory syncytial virus (RSV), the main cause of severe respiratory infections in infants, cannot be treated efficiently with antivirals. However, its RNA-dependent polymerase complex offers potential targets for RSV-specific drugs. This includes the recognition of its template, the r...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Ouizougun-Oubari, Mohamed, Pereira, Nelson, Tarus, Bogdan, Galloux, Marie, Lassoued, Safa, Fix, Jenna, Tortorici, M. Alejandra, Hoos, Sylviane, Baron, Bruno, England, Patrick, Desmaële, Didier, Couvreur, Patrick, Bontems, François, Rey, Félix A., Eléouët, Jean-François, Sizun, Christina, Slama-Schwok, Anny, Duquerroy, Stéphane
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2015
Θέματα:
Structure and Assembly
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621127/
https://ncbi.nlm.nih.gov/pubmed/26246564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01612-15
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