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Targeting ATR and Chk1 kinases for cancer treatment: A new model for new (and old) drugs

Trying to kill cancer cells by generating DNA damage is by no means a new idea. Radiotherapy and genotoxic drugs are routinely used in cancer therapy. More recent developments also explored the potential of targeting the DNA damage response (DDR) in order to increase the toxicity of radio‐ and chemo...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Toledo, Luis I., Murga, Matilde, Fernandez‐Capetillo, Oscar
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590794/
https://ncbi.nlm.nih.gov/pubmed/21820372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.07.002
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