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Targeting ATR and Chk1 kinases for cancer treatment: A new model for new (and old) drugs

Trying to kill cancer cells by generating DNA damage is by no means a new idea. Radiotherapy and genotoxic drugs are routinely used in cancer therapy. More recent developments also explored the potential of targeting the DNA damage response (DDR) in order to increase the toxicity of radio‐ and chemo...

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Dettagli Bibliografici
Autori principali: Toledo, Luis I., Murga, Matilde, Fernandez‐Capetillo, Oscar
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590794/
https://ncbi.nlm.nih.gov/pubmed/21820372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.07.002
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