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SIRT1 Positively Regulates Breast Cancer Associated Human Aromatase (CYP19A1) Expression

Breast cancer remains one of the leading causes of death in women diagnosed with cancer. In breast cancer, aberrant expression of the CYP19A1 gene, which encodes the aromatase enzyme, contributes to increased intratumoral levels of estradiol. Regardless of whether this estrogen is produced by periph...

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Bibliografiske detaljer
Main Authors: Holloway, Kimberly R., Barbieri, Andreia, Malyarchuk, Svitlana, Saxena, Madhurima, Nedeljkovic-Kurepa, Ana, Cameron Mehl, Mathieu, Wang, Allison, Gu, Xin, Pruitt, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589668/
https://ncbi.nlm.nih.gov/pubmed/23340254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1347
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