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Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Catenin in Breast Cancer Cells

The Wnt signaling pathway is often chronically activated in diverse human tumors, and the Frizzled (FZD) family of receptors for Wnt ligands, are central to propagating oncogenic signals in a β-catenin-dependent and independent manner. SIRT1 is a class III histone deacetylase (HDAC) that deacetylate...

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Detalhes bibliográficos
Main Authors: Simmons, Glenn E., Pandey, Somnath, Nedeljkovic-Kurepa, Ana, Saxena, Madhurima, Wang, Allison, Pruitt, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045932/
https://ncbi.nlm.nih.gov/pubmed/24897117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098861
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