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Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Catenin in Breast Cancer Cells

The Wnt signaling pathway is often chronically activated in diverse human tumors, and the Frizzled (FZD) family of receptors for Wnt ligands, are central to propagating oncogenic signals in a β-catenin-dependent and independent manner. SIRT1 is a class III histone deacetylase (HDAC) that deacetylate...

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Bibliografiske detaljer
Main Authors: Simmons, Glenn E., Pandey, Somnath, Nedeljkovic-Kurepa, Ana, Saxena, Madhurima, Wang, Allison, Pruitt, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045932/
https://ncbi.nlm.nih.gov/pubmed/24897117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098861
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