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Diverse Roles of SIRT1 in Cancer Biology and Lipid Metabolism

SIRT1, an NAD(+)-dependent deacetylase, has been described in the literature as a major player in the regulation of cellular stress responses. Its expression has been shown to be altered in cancer cells, and it targets both histone and non-histone proteins for deacetylation and thereby alters metabo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Simmons, Glenn E., Pruitt, Wendy M., Pruitt, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307284/
https://ncbi.nlm.nih.gov/pubmed/25569080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16010950
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