SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis

Distant metastasis is the main cause of breast cancer-related death; however, effective therapeutic strategies targeting metastasis are still scarce. This is largely attributable to the spatiotemporal intratumor heterogeneity during metastasis. Here we show that protein deacetylase SIRT7 is signific...

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Publicado no:Nat Commun
Main Authors: Tang, Xiaolong, Shi, Lei, Xie, Ni, Liu, Zuojun, Qian, Minxian, Meng, Fanbiao, Xu, Qingyang, Zhou, Mingyan, Cao, Xinyue, Zhu, Wei-Guo, Liu, Baohua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566498/
https://ncbi.nlm.nih.gov/pubmed/28827661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00396-9
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