SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling

Sirtuin 1 (SIRT1) is a class III histone deacetylase that deacetylates histone and nonhistone proteins to regulate gene transcription and protein function. Because SIRT1 regulates very diverse responses such as apoptosis, insulin sensitivity, autophagy, differentiation, and stem cell pluripotency, i...

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Autori principali: Holloway, Kimberly R., Calhoun, Tara N., Saxena, Madhurima, Metoyer, Cheynita F., Kandler, Ethan F., Rivera, Chantal A., Pruitt, Kevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889068/
https://ncbi.nlm.nih.gov/pubmed/20439735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911325107
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