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DVL1 and DVL3 differentially localize to CYP19A1 promoters and regulate aromatase mRNA in breast cancer cells

The CYP19A1 gene encodes aromatase, an enzyme that converts androgens into estrogens and consequently directly contributes to both the depletion of androgens and the synthesis of estrogens in several organs. Aromatase is critical for diverse biological processes such as proliferation, regulation of...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Castro-Piedras, Isabel, Sharma, Monica, den Bakker, Meghan, Molehin, Deborah, Martinez, Edgar G., Vartak, David, Pruitt, Wendy M., Deitrick, Jena, Almodovar, Sharilyn, Pruitt, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235026/
https://ncbi.nlm.nih.gov/pubmed/30479694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26257
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