DVL1 and DVL3 differentially localize to CYP19A1 promoters and regulate aromatase mRNA in breast cancer cells

The CYP19A1 gene encodes aromatase, an enzyme that converts androgens into estrogens and consequently directly contributes to both the depletion of androgens and the synthesis of estrogens in several organs. Aromatase is critical for diverse biological processes such as proliferation, regulation of...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Castro-Piedras, Isabel, Sharma, Monica, den Bakker, Meghan, Molehin, Deborah, Martinez, Edgar G., Vartak, David, Pruitt, Wendy M., Deitrick, Jena, Almodovar, Sharilyn, Pruitt, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235026/
https://ncbi.nlm.nih.gov/pubmed/30479694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26257
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