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Acetylation of conserved DVL-1 lysines regulates its nuclear translocation and binding to gene promoters in triple-negative breast cancer

Dishevelled (DVL) proteins are central mediators of the Wnt signalling pathway and are versatile regulators of several cellular processes, yet little is known about their post-translational regulation. Acetylation is a reversible post-translational modification (PTM) which regulates the function of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Sharma, Monica, Molehin, Deborah, Castro-Piedras, Isabel, Martinez, Edgar G., Pruitt, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838061/
https://ncbi.nlm.nih.gov/pubmed/31700102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52723-3
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