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TRIPTOLIDE INDUCES CELL DEATH IN PANCREATIC CANCER CELLS BY APOPTOTIC AND AUTOPHAGIC PATHWAYS

BACKGROUND & AIMS: Pancreatic adenocarcinoma, among the most lethal human malignancies, is resistant to current chemotherapies. We have previously shown that triptolide inhibits the growth of pancreatic cancer cells in vitro and prevents tumor growth in vivo. This study investigates the mechanis...

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書誌詳細
主要な著者: Mujumdar, Nameeta, MacKenzie, Tiffany, Dudeja, Vikas, Chugh, Rohit, Antonoff, Mara, Borja-Cacho, Daniel, Sangwan, Veena, Dawra, Rajinder, Vickers, Selwyn M., Saluja, Ashok K.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587769/
https://ncbi.nlm.nih.gov/pubmed/20434451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.04.046
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