TRIPTOLIDE INDUCES CELL DEATH IN PANCREATIC CANCER CELLS BY APOPTOTIC AND AUTOPHAGIC PATHWAYS

BACKGROUND & AIMS: Pancreatic adenocarcinoma, among the most lethal human malignancies, is resistant to current chemotherapies. We have previously shown that triptolide inhibits the growth of pancreatic cancer cells in vitro and prevents tumor growth in vivo. This study investigates the mechanis...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mujumdar, Nameeta, MacKenzie, Tiffany, Dudeja, Vikas, Chugh, Rohit, Antonoff, Mara, Borja-Cacho, Daniel, Sangwan, Veena, Dawra, Rajinder, Vickers, Selwyn M., Saluja, Ashok K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587769/
https://ncbi.nlm.nih.gov/pubmed/20434451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.04.046
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi