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Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells

Pancreatic cancer is a devastating disease with a survival rate of <5%. Moreover, pancreatic cancer aggressiveness is closely related to high levels of prosurvival mediators, which can ultimately lead to rapid disease progression. One of the mechanisms that enables tumor cells to evade cellular s...

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Detalhes bibliográficos
Main Authors: Mujumdar, Nameeta, Banerjee, Sulagna, Chen, Zhiyu, Sangwan, Veena, Chugh, Rohit, Dudeja, Vikas, Yamamoto, Masato, Vickers, Selwyn M., Saluja, Ashok K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042112/
https://ncbi.nlm.nih.gov/pubmed/24699326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00466.2013
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