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Primary and liver metastasis-derived cell lines from KRas(G12D); Trp53(R172H); Pdx-1 Cre animals undergo apoptosis in response to triptolide
OBJECTIVES: Pancreatic cancer has a five year survival rate of less than 5%, partly due to limited chemotherapeutic options, thereby highlighting the need for novel therapies. Triptolide, a diterpene triepoxide derived from a Chinese herb has shown great promise in preclinical testing against pancre...
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| Publicado no: | Pancreas |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412369/ https://ncbi.nlm.nih.gov/pubmed/25875797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000317 |
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