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Triptolide-induced Cell Death in Pancreatic Cancer Is Mediated by O-GlcNAc Modification of Transcription Factor Sp1

Pancreatic cancer, the fourth most prevalent cancer-related cause of death in the United States, is a disease with a dismal survival rate of 5% 5 years after diagnosis. One of the survival proteins responsible for its extraordinary ability to evade cell death is HSP70. A naturally derived compound,...

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Detalhes bibliográficos
Main Authors: Banerjee, Sulagna, Sangwan, Veena, McGinn, Olivia, Chugh, Rohit, Dudeja, Vikas, Vickers, Selwyn M., Saluja, Ashok K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837133/
https://ncbi.nlm.nih.gov/pubmed/24129563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500983
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