TRIPTOLIDE INDUCES CELL DEATH IN PANCREATIC CANCER CELLS BY APOPTOTIC AND AUTOPHAGIC PATHWAYS

BACKGROUND & AIMS: Pancreatic adenocarcinoma, among the most lethal human malignancies, is resistant to current chemotherapies. We have previously shown that triptolide inhibits the growth of pancreatic cancer cells in vitro and prevents tumor growth in vivo. This study investigates the mechanis...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mujumdar, Nameeta, MacKenzie, Tiffany, Dudeja, Vikas, Chugh, Rohit, Antonoff, Mara, Borja-Cacho, Daniel, Sangwan, Veena, Dawra, Rajinder, Vickers, Selwyn M., Saluja, Ashok K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587769/
https://ncbi.nlm.nih.gov/pubmed/20434451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.04.046
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