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Heat Shock Protein 70 Inhibits Apoptosis in Cancer Cells Through Simultaneous and Independent Mechanisms

BACKGROUND & AIMS: Heat shock proteins (HSPs) are highly conserved and serve a multitude of functions that mediate cell survival. HSP70, the only inducible form of the 70-kilodalton subfamily of HSPs, is overexpressed in pancreatic cancer cells and has been shown to inhibit caspase-dependent apo...

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Detalhes bibliográficos
Main Authors: DUDEJA, VIKAS, MUJUMDAR, NAMEETA, PHILLIPS, PHOEBE, CHUGH, ROHIT, BORJA–CACHO, DANIEL, DAWRA, RAJINDER K., VICKERS, SELWYN M., SALUJA, ASHOK K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896387/
https://ncbi.nlm.nih.gov/pubmed/19208367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.01.070
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