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Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ

Although amyloid β (Aβ) is a critical player in the pathology of Alzheimer’s disease, there is currently little Information on the rate and extent of formation of oligomers that lead to the presence of Aβ fibrils observed in amyloid plaques. Here we describe a unique method to monitor the full time...

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書誌詳細
主要な著者: Garai, Kanchan, Frieden, Carl
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587211/
https://ncbi.nlm.nih.gov/pubmed/23401512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222478110
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