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The association-dissociation behavior of the ApoE proteins: kinetic and equilibrium studies
The apolipoprotein E family consists of three major protein isoforms: apolipoprotein E4 (ApoE4), ApoE3 and ApoE2. The isoforms, which contain 299 residues, differ only by single amino acid changes but of the three only ApoE4 is a risk factor for Alzheimer’s Disease. At μM concentrations lipid-free A...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038193/ https://ncbi.nlm.nih.gov/pubmed/20923231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101407m |
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