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ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions
Apolipoprotein E gene (APOE) alleles may shift the onset of Alzheimer’s disease (AD) through apoE protein isoforms changing the probability of amyloid-β (Aβ) accumulation. It has been proposed that differential physical interactions of apoE isoforms with soluble Aβ (sAβ) in brain fluids influence th...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651443/ https://ncbi.nlm.nih.gov/pubmed/23620513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220484110 |
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