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Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ
Although amyloid β (Aβ) is a critical player in the pathology of Alzheimer’s disease, there is currently little Information on the rate and extent of formation of oligomers that lead to the presence of Aβ fibrils observed in amyloid plaques. Here we describe a unique method to monitor the full time...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587211/ https://ncbi.nlm.nih.gov/pubmed/23401512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222478110 |
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