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Valproic acid overcomes hypoxia-induced resistance to apoptosis

Valproic acid (VPA), a histone deacetylase inhibitor (HDACi), has been shown to be an effective tool in cancer treatment. Although its ability to induce apoptosis has been described in many cancer types, the data come from experiments performed in normoxic (21% O(2)) conditions only. Therefore, we q...

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書誌詳細
主要な著者: CIPRO, ŠIMON, HŘEBAČKOVÁ, JANA, HRABĚTA, JAN, POLJAKOVÁ, JITKA, ECKSCHLAGER, TOMÁŠ
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583540/
https://ncbi.nlm.nih.gov/pubmed/22159638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2011.1577
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