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The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells

Ellipticine is an antineoplastic agent, whose mode of action is based mainly on DNA intercalation, inhibition of topoisomerase II and formation of covalent DNA adducts mediated by cytochromes P450 and peroxidases. Here, the cytotoxicity of ellipticine to human neuroblastoma derived cell lines IMR-32...

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Bibliografiske detaljer
Main Authors: Poljaková, Jitka, Eckschlager, Tomáš, Hřebačková, Jana, Hraběta, Jan, Stiborová, Marie
Format: Artigo
Sprog:Inglês
Udgivet: Slovak Toxicology Society SETOX 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993486/
https://ncbi.nlm.nih.gov/pubmed/21218110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/v10102-010-0036-9
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