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Valproic acid overcomes hypoxia-induced resistance to apoptosis

Valproic acid (VPA), a histone deacetylase inhibitor (HDACi), has been shown to be an effective tool in cancer treatment. Although its ability to induce apoptosis has been described in many cancer types, the data come from experiments performed in normoxic (21% O(2)) conditions only. Therefore, we q...

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Detalhes bibliográficos
Main Authors: CIPRO, ŠIMON, HŘEBAČKOVÁ, JANA, HRABĚTA, JAN, POLJAKOVÁ, JITKA, ECKSCHLAGER, TOMÁŠ
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583540/
https://ncbi.nlm.nih.gov/pubmed/22159638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2011.1577
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