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Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes

Excess nicotinamide, a form of vitamin B(3), is metabolized through two enzymatic systems and eventually excreted from the body. The first system starts with the methylation of nicotinamide by nicotinamide N-methyltransferase, which can subsequently be oxidized by aldehyde oxidase. The second enzyma...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Real, Alexander Michael, Hong, Shangyu, Pissios, Pavlos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583486/
https://ncbi.nlm.nih.gov/pubmed/23418369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.049734
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