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Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes
Excess nicotinamide, a form of vitamin B(3), is metabolized through two enzymatic systems and eventually excreted from the body. The first system starts with the methylation of nicotinamide by nicotinamide N-methyltransferase, which can subsequently be oxidized by aldehyde oxidase. The second enzyma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583486/ https://ncbi.nlm.nih.gov/pubmed/23418369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.049734 |
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