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Variable contribution of CYP2D6 to the N-Dealkylation of S-(-)-propranolol by human liver microsomes
Recombinant cDNA expression systems for CYP2D6 have been shown to have significant catalytic activity with respect to the N-dealkylation of propranolol. However, the involvement of CYP2D6 in this reaction in human liver is inconclusive. We have re-evaluated the role of CYP2D6 in the dealkylation of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042674/ https://ncbi.nlm.nih.gov/pubmed/8877032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.43116.x |
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