Acamprosate suppresses magnetic resonance spectroscopy measures of central glutamate in detoxified alcoholics: A randomized controlled experimental medicine study

CONTEXT: Acamprosate is approved for treatment of alcoholism, but its mechanism of action remains unclear. Animal studies suggest that a persistent hyperglutamatergic state contributes to the pathophysiology of alcoholism, and that acamprosate may exert its actions by intervening in this process. Hu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Umhau, John C., Momenan, Reza, Schwandt, Melanie L., Singley, Erick, Lifshitz, Mariel, Doty, Linda, Adams, Lauren J., Vengeliene, Valentina, Spanagel, Rainer, Zhang, Yan, Shen, Jun, George, David T., Hommer, Daniel, Heilig, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583213/
https://ncbi.nlm.nih.gov/pubmed/20921123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2010.125
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi