Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate

Modulation of alcohol craving induced by challenge stimuli may predict the efficacy of new pharmacotherapies for alcoholism. We evaluated two pharmacological challenges, the α(2)-adrenergic antagonist yohimbine, which reinstates alcohol seeking in rats, and the serotonergic compound meta-chloropheny...

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Библиографические подробности
Главные авторы: Umhau, John C, Schwandt, Melanie L, Usala, Julie, Geyer, Christopher, Singley, Erick, George, David T, Heilig, Markus
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077446/
https://ncbi.nlm.nih.gov/pubmed/21289601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.253
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