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CHRONIC ALCOHOL NEUROADAPTATION AND STRESS CONTRIBUTE TO SUSCEPTIBILITY FOR ALCOHOL CRAVING AND RELAPSE

Alcoholism is a chronic relapsing disorder. Major characteristics observed in alcoholics during an initial period of alcohol abstinence are altered physiological functions and a negative emotional state. Evidence suggests that a persistent, cumulative adaptation involving a kindling/allostasis-like...

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Detalhes bibliográficos
Main Authors: BREESE, GEORGE R., SINHA, RAJITA, HEILIG, MARKUS
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026093/
https://ncbi.nlm.nih.gov/pubmed/20951730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2010.09.007
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