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Effects of naltrexone on neural and subjective response to alcohol in treatment-seeking alcohol dependent patients
RATIONALE: Positively reinforcing properties of alcohol are in part mediated by activation of the ventral striatum (VS). Alcohol-induced release of endogenous opioids is thought to contribute to this response. Preclinical studies show that the opioid antagonist naltrexone (NTX) can block this cascad...
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| Publicado no: | Alcohol Clin Exp Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4293087/ https://ncbi.nlm.nih.gov/pubmed/25581657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12581 |
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