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Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate

Modulation of alcohol craving induced by challenge stimuli may predict the efficacy of new pharmacotherapies for alcoholism. We evaluated two pharmacological challenges, the α(2)-adrenergic antagonist yohimbine, which reinstates alcohol seeking in rats, and the serotonergic compound meta-chloropheny...

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Bibliografski detalji
Glavni autori: Umhau, John C, Schwandt, Melanie L, Usala, Julie, Geyer, Christopher, Singley, Erick, George, David T, Heilig, Markus
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077446/
https://ncbi.nlm.nih.gov/pubmed/21289601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.253
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