TGF-β1–Containing Exosomes from Injured Epithelial Cells Activate Fibroblasts to Initiate Tissue Regenerative Responses and Fibrosis

Hypoxia is associated with tissue injury and fibrosis but its functional role in fibroblast activation and tissue repair/regeneration is unknown. Using kidney injury as a model system, we demonstrate that injured epithelial cells produce an increased number of exosomes with defined genetic informati...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Borges, Fernanda T., Melo, Sonia A., Özdemir, Berna C., Kato, Noritoshi, Revuelta, Ignacio, Miller, Caroline A., Gattone, Vincent H., LeBleu, Valerie S., Kalluri, Raghu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2013
विषय:
Brief Communications
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582210/
https://ncbi.nlm.nih.gov/pubmed/23274427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012101031
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