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Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity

The Stimulator of Interferon Genes (STING) pathway is implicated in the innate immune response and is important in both oncogenesis and cancer treatment. Specifically, activation of the cytosolic DNA sensor STING in antigen-presenting cells (APCs) induces a type I interferon response and cytokine pr...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: McAndrews, Kathleen M., Che, Sara P.Y., LeBleu, Valerie S., Kalluri, Raghu
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042450/
https://ncbi.nlm.nih.gov/pubmed/33711340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100523
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