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Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity

The Stimulator of Interferon Genes (STING) pathway is implicated in the innate immune response and is important in both oncogenesis and cancer treatment. Specifically, activation of the cytosolic DNA sensor STING in antigen-presenting cells (APCs) induces a type I interferon response and cytokine pr...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: McAndrews, Kathleen M., Che, Sara P.Y., LeBleu, Valerie S., Kalluri, Raghu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042450/
https://ncbi.nlm.nih.gov/pubmed/33711340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100523
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