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Structure and Dynamic Regulation of Abl Kinases

The c-abl proto-oncogene encodes a unique protein-tyrosine kinase (Abl) distinct from c-Src, c-Fes, and other cytoplasmic tyrosine kinases. In normal cells, Abl plays prominent roles in cellular responses to genotoxic stress as well as in the regulation of the actin cytoskeleton. Abl is also well kn...

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Библиографические подробности
Главные авторы: Panjarian, Shoghag, Iacob, Roxana E., Chen, Shugui, Engen, John R., Smithgall, Thomas E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581414/
https://ncbi.nlm.nih.gov/pubmed/23316053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.438382
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