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Structure and Dynamic Regulation of Abl Kinases

The c-abl proto-oncogene encodes a unique protein-tyrosine kinase (Abl) distinct from c-Src, c-Fes, and other cytoplasmic tyrosine kinases. In normal cells, Abl plays prominent roles in cellular responses to genotoxic stress as well as in the regulation of the actin cytoskeleton. Abl is also well kn...

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Detalhes bibliográficos
Main Authors: Panjarian, Shoghag, Iacob, Roxana E., Chen, Shugui, Engen, John R., Smithgall, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581414/
https://ncbi.nlm.nih.gov/pubmed/23316053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.438382
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