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Conformational disturbance in Abl kinase upon mutation and deregulation
Protein dynamics are inextricably linked to protein function but there are few techniques that allow protein dynamics to be conveniently interrogated. For example, mutations and translocations give rise to aberrant proteins such as Bcr-Abl where changes in protein conformation and dynamics are belie...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635808/ https://ncbi.nlm.nih.gov/pubmed/19164531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811912106 |
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