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NKT associated Hedgehog and Osteopontin drive fibrogenesis in nonalcoholic fatty liver disease

Immune responses are important in dictating nonalcoholic steatohepatitis (NASH) outcome. We previously reported that upregulation of hedgehog (Hh) and osteopontin (OPN) occurs in NASH, that Hh-regulated accumulation of natural killer T (NKT) cells promotes hepatic stellate cell (HSC) activation, and...

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מידע ביבליוגרפי
Main Authors: Syn, Wing-Kin, Agboola, Kola M, Swiderska, Marzena, Michelotti, Gregory, Liaskou, Evaggelia, Pang, Herbert, Xie, Guanhua, Philips, George, Chan, Isaac S, Karaca, Gamze F, Pereira, Thiago A, Chen, Yuping, Mi, Zhiyong, Kuo, Paul C, Choi, Steve S, Guy, Cynthia D, Abdelmalek, Manal F, Diehl, Anna Mae
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578424/
https://ncbi.nlm.nih.gov/pubmed/22427237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2011-301857
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