NKT associated Hedgehog and Osteopontin drive fibrogenesis in nonalcoholic fatty liver disease

Immune responses are important in dictating nonalcoholic steatohepatitis (NASH) outcome. We previously reported that upregulation of hedgehog (Hh) and osteopontin (OPN) occurs in NASH, that Hh-regulated accumulation of natural killer T (NKT) cells promotes hepatic stellate cell (HSC) activation, and...

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Bibliographic Details
Main Authors:	Syn, Wing-Kin, Agboola, Kola M, Swiderska, Marzena, Michelotti, Gregory, Liaskou, Evaggelia, Pang, Herbert, Xie, Guanhua, Philips, George, Chan, Isaac S, Karaca, Gamze F, Pereira, Thiago A, Chen, Yuping, Mi, Zhiyong, Kuo, Paul C, Choi, Steve S, Guy, Cynthia D, Abdelmalek, Manal F, Diehl, Anna Mae
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3578424/ https://ncbi.nlm.nih.gov/pubmed/22427237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2011-301857
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NKT associated Hedgehog and Osteopontin drive fibrogenesis in nonalcoholic fatty liver disease

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